All eyes will be on Santiago Bernabeu this weekend, as Real Madrid host their local rivals Atletico Madrid on Sunday.
Barcelona will look to take another step towards the league title when they host 14th-placed Leganes on the same day.
To help you out with your team selection this week, we have drafted our best XI for the upcoming week:
Goalkeeper: Marc ter Stegen (Barcelona)
Barcelona are at home against Leganes this weekend, so we expect the German to keep a clean sheet. He is available for 7.5m in the market.